Fibroblast Reprogramming in Gastrointestinal Cancer
نویسندگان
چکیده
منابع مشابه
Defined factors induce reprogramming of gastrointestinal cancer cells.
Although cancer is a disease with genetic and epigenetic origins, the possible effects of reprogramming by defined factors remain to be fully understood. We studied the effects of the induction or inhibition of cancer-related genes and immature status-related genes whose alterations have been reported in gastrointestinal cancer cells. Retroviral-mediated introduction of induced pluripotent stem...
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The use of reprogramming technologies have been developed to revert normal somatic differentiated cells (NSDCs), such as fibroblasts, into patient-specific induced-pluripotent stem cells (iPSCs) that can be easily differentiated into different lineages, potentially useful in cell therapy and regenerative medicine. The method invented by Yamanaka [1] allows inserting into the cell, by plasmid tr...
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ژورنال
عنوان ژورنال: Frontiers in Cell and Developmental Biology
سال: 2020
ISSN: 2296-634X
DOI: 10.3389/fcell.2020.00630